Stem cell therapy involves the use of stem cells to treat or prevent a disease or condition. The most widely used stem cell therapy is bone marrow transplantation, but some therapies are also used from umbilical cord blood. Research is underway to develop different sources of stem cells, as well as to apply stem cell therapy to neurodegenerative diseases (neurology or neurosurgery categories), including diabetes and heart disease.
Stem cell therapy has become controversial as a result of developments such as the ability of scientists to isolate and culture embryonic stem cells, to create stem cells using somatic cell nuclear, and to use techniques to create new cells. induced pluripotent stem cells.
Stem cells have been shown to be extremely promising in helping people develop a wealth of knowledge to understand and treat a range of diseases, injuries and other health problems. Their potential is evident in the use of blood stem cells in the treatment of blood disorders, a therapy that has saved the lives of thousands of children with leukemia; and can be seen in the use of stem cells for tissue transplantation for the treatment of diseases or lesions of bones, skin and the surface of the eyes.
Stem cells therapies refer to many medical categories such as ophtalmology, cardiology, dermatology, gastroenterology, gynecology, oncology but also orthopedics, plastic surgery (body or face) and even spine surgery.
1. Anti-aging - stem cells
Using stem cells to slow down aging more effectively and reverse the signs of aging is not a new idea, it is increasingly known to the general public.
Stem cell anti-aging therapy is the most advanced and modern approach available to slow or reverse the aging process of the population. In addition, anti-aging stem cell therapy helps strengthen the remaining cells so they can last a very long time.
Aging is a very natural, but surprisingly complex process that everyone participates in as they get older. The aging process is one in which the cells of the body are gradually damaged as a result of normal wear and tear. Finally, these cells die. Some cells are replaced as they die, but it's never fast enough to fully compensate for cell death. As a result, signs of aging begin to appear. New stem cells and associated therapies are very useful for slowing down or, in some cases, even reversing this natural aging process.
How anti-stem cell treatment works
The anti-aging treatment of the stem cells is performed as an outpatient and does not require any post-operative unavailability. The strict guidelines of the FDA are monitored when therapies such as anti-aging therapy involve minimal manipulation of mesenchymal stem cells (MSCs). The stem cells must be the patient's own stem cells and must be returned to the patient immediately after the end of the treatment.
Therapy begins with the harvesting of adipose tissue. The small sample is then centrifuged to separate MSCs from other adipose tissue components. This process helps stem cells to be highly concentrated. As such, this concentrate serves as a base for the serum and is reinjected to the patient as soon as the MSCs are processed.
All therapy is completed within a few hours and patients can return home and resume normal activities immediately after leaving the clinic. It is rarely necessary to take pain medication after the procedure. Otherwise, it is generally reported that mild to moderate discomfort occurs at the cell collection site.
2. Autistic brain repair - stem cell
Autism is a spectrum of disorders characterized by marked anomalies in communication and social interactions. In children with this disorder, there are usually two consistent findings: reduction of oxygen in certain areas of the brain, and an inflammatory, immune mediated inflammatory condition in the intestine.
How do stem cells help people with autism?
In autism, stem cell therapy is primarily designed to treat problems related to the immune system, the neurological system and the digestive system.
- It is known that stem cells can regulate the immune system by secreting specific cytokines (cytokines are substances that allow cells to communicate with other cells), which regulate the expression of inflammatory substances and negatively regulate the system. im
- It is known that stem cells can regulate the immune system by secreting specific cytokines (cytokines are substances that allow cells to communicate with other cells), which regulate the expression of inflammatory substances and negatively regulate the system. immune.
- In terms of the intestine, stem cells arrive at certain parts of the intestinal mucosa, where permeability is a problem and help restore the spaces between each cell, thus preventing the escape of foreign substances (which cause inflammation) into the blood .
- In the central nervous system, stem cells can help the brain recover some of its plasticity by reconnecting clusters of specific neurons and facilitate the "installation" of new behaviors.
3. Brain Treatment - Stem Cells
With the help of stem cells, it is possible to recover from a brain injury. Regardless of the time of the injury, the stem cell transplant progressively restores the functions lost after the injury.
It has long been considered that damaged neurons are irreplaceable. Recent research has revealed that the brain has a particular domain in which the primary role is to produce neurons.
4. Cerebral palsy - Stem cells
Cerebral palsy is a condition that causes wounds or brain abnormalities, usually in the uterus, but occurs at any time during the first two years after delivery. It affects the functions of the brain and the nervous system, such as thinking, seeing, listening, learning and moving.
The most common causes of hypoxia (lack of oxygen), head trauma, maternal infections such as rubella, cerebral bleeding, brain infection and severe jaundice. PC types include ataxic, hypotonic, spastic, dyskinetic and mixed.
Can cerebral palsy be treated with stem cells?
Umbilical cord mesenchymal stem cells are considered universal donor cells because they are not immediately recognized as foreign. The cells harbor damaged tissues and are known to secrete molecules called trophic factors.
The trophic factors of mesenchymal stem cells are known to stimulate the repair of damaged nerve tissue in the brain and spinal cord. Some of these neurotrophic factors that stimulate neuronal growth to cause the growth of new blood vessels, neurogenesis and astroglial activation, promote synaptic connections and axonal remyelination, decrease programmed cell death, and regulate microglial activation.
Mesenchymal stem cells stimulate brain repair after stroke and traumatic brain injury.
Animal studies show that mesenchymal stem cells can migrate to the brain and survive.
There is evidence to support the belief that mononuclear bone marrow derived cells are safe and improve the quality of life of children with neurological disorders, including cerebral palsy.
5. Treatments for Heart Disease - Stem Cells
What is heart failure?
Heart failure is a condition in which the heart can not pump enough blood throughout the body to function normally. This can occur as a result of a functional or structural heart disorder. Cardiomyopathy, hypertension, heart valve problems and coronary artery disease are common causes of heart failure.
With regard to the heart, a stem cell can not only penetrate the damaged areas but also trigger a cascade of biological events that can lead to healing of the heart muscle. For example, animal studies have shown that stem cell therapy would lead to the creation of new muscle cells by stimulating dormant stem cells already present in the heart muscle.
What types of stem cells are used to treat heart failure and how are they collected?
Adult stem cells used to treat heart failure are derived from human umbilical cord tissue (allogeneic mesenchymal). These stem cells have been developed in any state-of-the-art laboratory.
What are the benefits of treating failure help with allogeneic stem cells derived from umbilical cord tissue?
Stem cells with the best anti-inflammatory activity, immune modulation capacity and regenerative pacing ability can be researched and selected.
Allogeneic stem cells may be administered several times daily in single doses containing a large number of cells.
The umbilical cord of the tissue is an abundant source of mesenchymal stem cells.
It is not necessary to collect stem cells from the patient's hip or fat under anesthesia, which can be particularly uncomfortable for young children and their parents.
It is increasingly evident that mesenchymal stem cells derived from the umbilical cord are more robust than mesenchymal stem cells from other sources.
It is not necessary to administer chemotherapy drugs such as granulocyte colony stimulating factor (G-CSF or GCSF) to stimulate the bone marrow to produce granulocytes and stem cells and release them in the blood.
The use of stem cells to treat or prevent a disease or condition is called stem cell therapy. It is widely used in some areas, including heart disease treatments, cerebral palsy, brain treatments, autistic brain repair and anti-aging treatment.